Yes, according to the New Yorker:
Now the South is becoming isolated again. Every demographic and political trend that helped to re-elect Barack Obama runs counter to the region’s self-definition: the emergence of a younger, more diverse, more secular electorate, with a libertarian bias on social issues and immigration; the decline of the exurban life style, following the housing bust; the class politics, anathema to pro-business Southerners, that rose with the recession; the end of America’s protracted wars, with cuts in military spending bound to come. The Solid South speaks less and less for America and more and more for itself alone.
Solidity has always been the South’s strength, and its weakness. The same Southern lock that once held the Democratic Party now divides the Republican Party from the socially liberal, fiscally moderate tendencies of the rest of America. The Southern bloc in the House majority can still prevent the President from enjoying any major legislative achievements, but it has no chance of enacting an agenda, and it’s unlikely to produce a nationally popular figure.